T Activation in a Patient with T Cell Chronic Lymphatic Leukemia

Prolonged Vincristine Toxicity Induced by Concurrent Posaconazole in a Child with T-cell Acute Lymphoblastic Leukemia

Specific cutaneous manifestations in adult T cell leukemia/lymphoma

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...

Decreased CD45RA T Cells in B-Cell Chronic Lymphatic Leukemia Patients: Correlation With Disease Stage

T-cell subsets CD4, CD8 and suppressor-inducers (CD45RA) were determined in 20 patients with B-cell chronic lymphatic leukemia (B-CLL). The proportion of CD4 and CD45RA was decreased when compared with T cells from normal subjects. CD8 was markedly increased. The activity of concanavalin A-induced suppressor cells was not significantly different from that of normal controls and was negatively c...

Decreased CD45RA T cells in B-cell chronic lymphatic leukemia patients: correlation with disease stage.

T-cell subsets CD4, CD8 and suppressor-inducers (CD45RA) were determined in 20 patients with B-cell chronic lymphatic leukemia (B-CLL). The proportion of CD4 and CD45RA was decreased when compared with T cells from normal subjects. CD8 was markedly increased. The activity of concanavalin A-induced suppressor cells was not significantly different from that of normal controls and was negatively c...

Chronic T-cell Leukemia/Lymphoma.

This issue of Cancer Control focuses on the clinicopathologic features of chronic T-cell leukemia/ lymphoma. Chronic leukemia of T-cell origin was first identified by Brouet and colleagues in 1975. Several classification systems for T-cell lymphoid malignancies have been proposed since then. The French-American-British (FAB) Cooperative Group’s proposal for classification designated four subgro...